Pediatric Diffuse Gliomas | A Master Class
Pediatric Low-Grade Gliomas | Part 1
Part 1 of the Pediatric Low-Grade Gliomas series focuses on distinguishing pediatric-type diffuse low-grade gliomas from adult diffuse gliomas, including cases in adolescent and teenage patients, where diagnostic overlap is common.
The discussion centers on pediatric-type diffuse astrocytomas, particularly MYB- and MYBL1-altered tumors, highlighting their biologic behavior, radiologic characteristics, and how they differ from adult-type diffuse gliomas despite similar imaging appearances.
Pediatric Low-Grade Gliomas | Part 2
Part 2 of the Pediatric Diffuse Low-Grade Gliomas series focuses on angiocentric glioma and other long-term epilepsy-associated tumors (LEATs), with an emphasis on their clinical behavior, radiologic features, and surgical implications.
The discussion explores why certain pediatric diffuse low-grade gliomas present predominantly with epilepsy, how angiocentric glioma fits within the spectrum of pediatric-type diffuse gliomas, and how these tumors differ biologically and prognostically from adult diffuse gliomas.
Pediatric Low-Grade Gliomas | Part 3
Part 3 of the Pediatric Diffuse Low-Grade Gliomas series focuses on PLNTY (Polymorphous Low-Grade Neuroepithelial Tumor of the Young) and related epilepsy-associated pediatric tumors, with an emphasis on their epileptogenic behavior and surgical implications.
The discussion explores why certain pediatric low-grade tumors present primarily with seizures, how PLNTY fits within the spectrum of pediatric-type diffuse gliomas and LEATs, and how these tumors differ from both adult diffuse gliomas and other epilepsy-associated lesions.
Pediatric Diffuse Gliomas | MAPK Altered & DMG
This session in the Pediatric Diffuse Gliomas series focuses on MAPK pathway–altered gliomas and diffuse midline gliomas (DMG), highlighting their biologic behavior, molecular underpinnings, and clinical implications in pediatric and adolescent patients.
The discussion explores how MAPK-altered tumors differ from other pediatric diffuse gliomas, why molecular classification is central to diagnosis and prognosis, and how these tumors may present across a wide age spectrum with variable radiologic appearances.
Pediatric High Grade Gliomas | Part 2
This session on Pediatric High-Grade Gliomas focuses on the biologic and clinical distinctions between pediatric and adult high-grade gliomas, emphasizing why pediatric tumors represent a fundamentally different disease entity rather than a younger presentation of adult glioblastoma.